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  4. SFT - Theriogenology Annual Conference - Bellevue, 2022
  5. Effect of endocrinopathies on fertility in the mare Part 2: Pituitary pars intermedia dysfunction
SFT - Theriogenology Annual Conference
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Effect of endocrinopathies on fertility in the mare
Part 2: Pituitary pars intermedia dysfunction

Author(s):

Maria Cadario, Louis Archbald

In: SFT - Theriogenology Annual Conference - Bellevue, 2022 by Society for Theriogenology
Updated:
JAN 10, 2023
Languages:
  • EN
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    Due to advances in veterinary medicine, equine geriatric population has markedly increased. Without losing perspective of the reproductive problems associated with ageing, it is very important to consider the endocrinologic/metabolic problems (e.g., pituitary pars intermedia dysfunction [PPID; i.e., equine Cushing’s disease]) that may also directly impact fertility in this group. PPID is neurological in origin and negatively affects mare’s fertility. Frequent clinical signs are: older mare with abnormal, ectopic fat deposits, hirsutism, abnormal estrous cycles, anovulatory follicles, frequent or persistent endometritis, and laminitis. A large number of mares with PPID may develop insulin dysregulation (ID) and insulin resistance (IR) due to the persistent hyperglycemia resulting in ectopic fat deposits or the genetic link that PPID shares with equine metabolic syndrome. Diagnosis of PPID requires a detailed history and physical evaluation combined with appropriate laboratory tests. Treatment for PPID comprises good management and treatment with either dopamine agonists (pergolide, cabergoline) or cyproheptadine, or a combination. A few studies linked or associated subfertility with this condition, and clearly, there is a need for further investigation. ...

    Age, insulin dysregulation, mare, fertility, hirsutism

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    Society for Theriogenology

    The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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