Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Approach to the Diagnosis and Management of Chronic Enteropathies (Part I and II)
Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Read
Chronic enteropathy (CE) is an umbrella term that encompasses three forms of chronic diarrhea in dogs and cats: antibiotic-responsive diarrhea (ARD), food-responsive diarrhea (FRD), and steroid/immunosuppressive drug-responsive diarrhea (SRD), with the latter also being termed (idiopathic) inflammatory bowel disease. Of these, food-responsive diarrhea was documented in 131/203 dogs (64%) with chronic enteropathies in a recent study1 making it the most common form of CE in dogs. The underlying pathogenesis of FRD is unknown, but the condition has been associated with intestinal immune-mediated inflammation. Other possible contributors include genetic and environmental factors, such as diet and the intestinal microbiome. NF-κB expression is upregulated in the duodenum of dogs with both food-responsive diarrhea and steroid-responsive diarrhea. Normal TLR4 and TLR5 function is important in the defense against intestinal bacterial invasion and in maintaining intestinal homeostasis. There appears to be a polymorphism of the gene encoding for TLR4 and TLR5 in German shepherd dogs with FRD and other forms of idiopathic CE. Dogs with either FRD or SRD also have an increase in serum IgE and IgG against a wide spectrum of food antigens, with substantial overlap between the two groups. [...]
Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Comments (0)
Ask the author
0 comments