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Management of Multiresistant Pathogens
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Introduction
While multidrug resistant infections can be somewhat intimidating, the general concepts of treatment are the same regardless of whether the infection is caused by a highly susceptible or highly resistant microorganism. Typically, resistant bacteria are no more virulent than susceptible bacteria, with the key determinant of successful outcome being prompt identification of the infection and an appropriate treatment, instead of whether the pathogen is highly resistant or susceptible. However, the potentially limited antibiotic options for some resistant infections can pose great challenges and ultimately impact outcome.
Systemic antibiotic therapy
For most infections, systemic antimicrobials are required. Drugs may be limited but typically one or more viable options are identified. Expanded susceptibility panels can often be requested from laboratories. At times, consultation with an expert in infectious diseases and antimicrobial therapy may be indicated to determine the optimal approach. However, even with highly resistant microorganisms, some commonly used drugs may be effective. It is important to remember that just because a bacterium is multidrug resistant, it does not mean that newer drugs are always required. [...]
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