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The Importance of MRSA and Multiresistant Pathogens
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Introduction
While the early ‘antibiotic era’ heralded widespread optimism and an assumption that infectious diseases had been conquered, it is clear that we are now struggling to maintain control over the microbial world that we live amongst. Antimicrobials are among the most important advances of modern medicine and have had profound impacts on morbidity and mortality, yet bacteria have demonstrated a high degree of tenacity in the face of antimicrobial challenge, with emergence of antimicrobial resistance posing a major challenge to modern medicine. Multidrug-resistant (MDR) pathogens of many types have become well established in human and animal populations, in part from excessive antimicrobial use, and transmission of certain MDR pathogens between animals and humans is of increasing concern.
Impact and concerns
Multidrug-resistant pathogens are of concern for both equine and human health. While resistant pathogens tend to be no more virulent than their susceptible counterparts, treatment options may be limited and empirical therapy may fail, thereby potentially worsening the outcome and complicating treatment. Outbreaks of MDR infections can occur in equine hospitals and on farms. Further, zoonotic transmission is of concern for some MDR pathogens, with human health concerns mimicking those in horses: infections that are resistant to empirical therapy and they may be difficult to treat. Multidrug-resistant pathogens include both rare and endemic bacteria, along with established and emerging issues. [...]
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