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3 Double-Blind Studies Comparing C0² Laser and Scalpel on Pain and Healing
Pedro Azevedo
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The study based on dog model animal, aims to evaluate if there are differences in the hemodynamic responses between patients submitted to skin incision with a blade scalpel and with a CO2 laser, using measurement changes in heart rate (HR) and arterial blood pressure (ABP) (including systolic-SAP, diastolic-DAP, and median-MAP) associated with different patient pain level perceptions during surgical procedures. A sample of 50 dogs (N=50) of both genders, aged between one and five years, with no cardiovascular diseases, but with a soft tissue surgical clinical condition was used. The sample was divided into two groups each comprising 25 individuals. One group had midline skin incisions made with a scalpel (GS), and the other had midline skin incisions made with a CO2 laser (GL), specifically an Aesculight®. The study design considered only one surgical time point, T1 (midline skin incision), at which HR and ABP-SAP, DAP, and MAP-were measured using a high definition oscillometry (HDO) device, which allowed a fast and accurate read of the parameters. For statistical analysis, P-values<0.05 were considered significant. All the patients presented the same pattern variation for the HR and ABP, with lower values being recorded for patients which had the midline skin incision made with the CO2- laser. The variations between GL and GS were statistically significant with a value of P< 0.001 for all the ABP parameters, but not for HR (P=0.12). O [...]
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Affiliation of the authors at the time of publication
Anjos of Assis Veterinary Medicine Centre – Barreiro Portugal
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