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Evaluating transdermal flunixin-meglumine in treatment for white line disease in dairy cows
Roger Bellet Elias and Gerard...
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Objective
To evaluate the effect of transdermal flunixin-meglumine on healing and reproductive performance in lactating dairy cows with white line disease (WLD).
Material and methods
The study was performed in a commercial dairy farm with 2.500 lactating cows in the North East of Spain in 2019. Cows were included in the study if they had WLD in one hoof (cows were excluded if they had other hoof lesions), 0 - 120 days in milk and no other health problems (mastitis, metritis, etc.) or medical treatment in the 30 days prior enrollment. The day of enrollment (day 0) a functional trimming for the WLD affected hoof and a block treatment for the healthy hoof was performed in all cows. Additionally, cows were randomized into one of both treatment groups: anti-inflammatory treatment with a single dose of flunixin pour-on administered on day 0 (group FTD, Finadyne® Transdermal 50 mg/ml, MSD AH) or without anti-inflammatory treatment (control group). Cows were re-evaluated in the hoof trimming chute between Day 7 to 21 after enrollment. The progress of the lesion was considered as healing if the hoof was reconstructed and no blood was present. Additionally, conception rate was evaluated for animals inseminated between -30 to +60 d of enrolment (n=31). The following data was recorded for each animal: days in milk, parity (primiparous vs. multiparous), affected limb (fore vs. hind limb) and hoof (medial vs. lateral), size of the lesion depending on the size (small vs. large), healing rate and conception rate. Data were analyzed by Chi square ́s test using SPSS 18.0 (SPSS, Chicago, USA). [...]
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