Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Strangles Update
Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Read
Strangles remains a major infectious threat to horses world-wide. The disease manifests in a variety of well recognised clinical syndromes and the epidemiological studies that have been undertaken over the last 10 years have identified a significant role for the carrier horse. Streptococcus equi var equi is a primary pathogen and its detection in any horse is always significant. There is no significant commensal state – wherever it is found it is either in carrier recovered horse or in a clinically significant state. The related organism Streptococcus equi var zooepidemicus is a common equine commensal both on the skin and within the airways. It causes a condition that can be termed “False Strangles” – some of the signs are similar but the disease is invariably far less severe and is invariably a sequel to other respiratory tract infections (virus or bacteria) or immunocompromising states.
Streptococcus equi var equi is a Gram positive, Lancefield group C, chain forming coccus. Interestingly the chains are shorter in abscesses than they are in cultures. Culture on blood agar shows wide zones of beta haemolysis and many isolates grow as capsulated, mucoid colonies. Some are however less capsulated or even acapsular and produce matt colonies.
The organism is highly contagious with a potential 80% or more attack rate on contact susceptible horses. Spread from horse to horse is by fomites or aerosol spread. Susceptibility to the infection is variable and highly dependent on the extent of previous exposure and the immune status of the horse.
Key stages in the pathogenesis of Strangles include:
- Colonization of URT epithelium
- Epithelial invasion / entry to lamina propria
- Entry into lymphatics ± circulating blood
- Persist despite neutrophil chemotaxis / phagocytosis
- Abscessation (LN / other organs). [...]
Get access to all handy features included in the IVIS website
- Get unlimited access to books, proceedings and journals.
- Get access to a global catalogue of meetings, on-site and online courses, webinars and educational videos.
- Bookmark your favorite articles in My Library for future reading.
- Save future meetings and courses in My Calendar and My e-Learning.
- Ask authors questions and read what others have to say.
Comments (0)
Ask the author
0 comments