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Inflammatory Changes of Adipose Tissue and Pancreatitis in Cattle with Fat Necrosis
Urushizaki S.
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Objectives:
Fat necrosis in cattle is characterized by necrotic tissue in the fat deposits of abdominal cavity. Previous studies have indicated that obesity resulting from excessive energy intake in the growing stage and subsequent disturbances in lipid metabolism are related to occurrence of fat necrosis. However, the etiology of this disease in cattle is not well understood. On the other hand, it has previously been reported that adipose tissue is an important endocrine organ that secretes a large number of adipocytokines, which may be involved in a variety of physiologic and pathologic processes. Evidence has accumulated indicating that obesity is associated with a state of chronic low-grade inflammation in adipose tissue. Moreover, there is also considerable report indicating that cattle with fat necrosis tended to have more severe pancreatitis than those without fat necrosis. In this study, we examined the relationship between adipose tissue inflammation, pancreatitis and fat necrosis in cattle. […]
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Affiliation of the authors at the time of publication
University of Miyazaki, Miyazaki, Japan
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