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L'alopecia endocrina nel cane
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Introduzione
Il follicolo pilifero è influenzato dall'attività ormonale in una varietà di modi ed è capace di per sé di sintetizzare e convertire una vasta gamma di ormoni. Nel ratto, è stato dimostrato che l'estradiolo, il testosterone e gli steroidi prodotti dalle ghiandole surrenali ritardano l'inizio della fase anagena (crescita attiva), mentre gli ormoni tiroidei accelerano l'attività follicolare (1). Nel cane, alcune endocrinopatie (ipotiroidismo, ipercortisolismo), neoplasie funzionale delle gonadi (iperestrogenismo) e displasie del follicolo (alopecia ciclica dell'inguine) sono associate ad alterazioni del ciclo follicolare e si presentano con un'alopecia simmetrica.
Lo scopo di questo articolo è fornire una sintesi aggiornata sulla patogenesi e sui segni dermatologici delle malattie ormonali che causano alterazioni del ciclo follicolare e offrire un approccio diagnostico per i cani con alopecia simmetrica non pruriginosa. [...]
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