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Epidemiología clínica - análisis de enzimas hepáticas
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Introducción
Existe poca bibliografía sobre la sensibilidad, la especificidad y valor predictivo de los valores de actividad de las enzimas hepáticas. Los valores de la alanina aminotransferasa (ALT) canina han indicado una sensibilidad que oscila entre el 45% y 100%, dependiendo de la patología hepática (enfermedad hepática aguda o crónica, etc...) (1). El valor predictivo citado para la medición de la actividad de la ALT en este artículo fue del 18%, es decir, un aumento de la ALT es predictivo de patología hepática para 1 de cada 5 pacientes. La especificidad de la fosfatasa alcalina (ALP) canina oscilaba entre el 44% y el 90%, dependiendo de la enfermedad hepática en cuestión. Su valor predictivo era del 21%, siendo bastante similar al de la ALT. En general, estas pruebas no son ideales para establecer un diagnóstico definitivo y es esencial que vayan acompañadas de pruebas más específicas. En este artículo, describimos los resultados de la base de datos Banfield para los análisis de las enzimas hepáticas, de manera específica para perros y gatos supuestamente sanos en la visita veterinaria. [...]
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