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Evaluating the reliability of computed tomography for the diagnosis of intervertebral disc extrusion in dogs
Cloe Smith
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PICO question
In dogs with an acute thoracolumbar myelopathy, is non-contrast computed tomography (CT) a reliable method for the diagnosis of intervertebral disc extrusion, compared to magnetic resonance imaging (MRI)?
Clinical bottom line
Category of research question
Diagnosis
The number and type of study designs reviewed
Four papers were critically reviewed. Two were retrospective, cross-sectional studies, and two were prospective, observational cohort studies
Strength of evidence
Moderate
Outcomes reported
The current literature suggests that CT is often sufficient for the diagnosis of thoracolumbar intervertebral disc extrusion, with MRI superior to CT for lesion characterisation. Non-contrast CT is likely sufficient for the diagnosis and surgical planning for intervertebral disc disease in Dachshunds. However, MRI is recommended for diagnosis and surgical planning of thoracolumbar intervertebral disc disease in non-Dachshund breeds
Conclusion
Computed tomography is often sufficient for the diagnosis of thoracolumbar intervertebral disc extrusion. However, MRI is superior to CT for lesion characterisation and it is therefore recommended to use MRI for cases requiring surgical planning. Computed tomography is likely sufficient for the diagnosis and surgical planning of intervertebral disc disease in Dachshunds
Regard for the reason of diagnostics performed (e.g. surgical planning) and the likelihood of other differential diagnoses (e.g. spinal neoplasms) should be taken before deciding to use one imaging modality over the other. Consideration into the risks associated with anaesthetising an animal with a spinal cord lesion, the ability of the practitioner to accurately localise the myelopathy and interpret the results, should be taken before pursuing diagnostics in these cases
How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
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Appraisal, application and reflection
The literature search performed found four papers which addressed, or partially addressed the PICO.
MRI was found to have an increased sensitivity for the detection of intervertebral disc disease in dogs, compared to non-contrast CT (Cooper et al., 2014; and Noyes et al., 2017). However low-field MRI misdiagnosed all cases of thoracolumbar intradural disc herniation when compared with CT myelography in dogs (Tamura et al., 2015).
Non-contrast CT appears to be a sufficient imaging modality for intervertebral disc disease and surgical planning in the majority of Dachshunds (96.4%; 323/335) (Emery et al., 2018).
Regard for the reason for diagnostics performed (e.g. surgical planning) and the likelihood of other differential diagnoses (e.g. spinal neoplasms) should be taken before deciding to use one imaging modality over the other. Cost, procedure time, and need for a general anaesthetic are also factors that should be considered when assessing between MRI and CT examinations.
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