8 ISO Prostaglandin F2α Is Produced During in vitro Incubation of Stallion Spermatozoa and Correlates with Sperm Death

Although the generation of reactive oxygen species (ROS) is required for numerous normal sperm physiologic functions, oxidative stress occurs when endogenous antioxidants and oxygen scavengers are overwhelmed by ROS, resulting in cellular injury and cell death. Moreover current sperm technologies in the functionality of the male gamete, involves different forms of oxidative stress. Reactive oxygen species have been largely considered a detrimental factor, but recent research challenges this assumption. [...]