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  4. SFT - Theriogenology Annual Conference - Portland, 2014
  5. Immunology and Immunomodulation of the Reproductive Tract
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Immunology and Immunomodulation of the Reproductive Tract

Author(s):
Morresey P.R.
In: SFT - Theriogenology Annual Conference - Portland, 2014 by Society for Theriogenology
Updated:
AUG 09, 2014
Languages:
  • EN
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    Introduction
    Persistent endometritis is a major cause of reproductive wastage and hence economic loss to the equine breeding industry. The endometrium of the mare is periodically exposed to numerous irritants and potentially infectious agents during breeding, iatrogenically during veterinary procedures, and when normal defense mechanisms become incompetent.

    Multiple physical and functional barriers exist to prevent or minimize contamination between episodes of breeding and during pregnancy. Once introduced to the endometrium infectious agents encounter both innate and adaptive immune defenses consisting of both cellular and humoral factors. Components include the epithelial mucus barrier, resident innate immune cells, and their proinflammatory secretions that minimize the risk of infection. Acting in concert with the innate immune system, the adaptive immune system includes both cell-mediated and humoral responses generated towards specific pathogens. Cells of the innate and adaptive immune systems are influenced by the ovarian sex hormones, local growth factors, and the commensal genital tract flora. Much of what is known has been determined from laboratory species, humans and production animals. In the current review, this will be extrapolated to the horse where applicable. […]

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    How to reference this publication (Harvard system)?

    Morresey, P. (2014) “Immunology and Immunomodulation of the Reproductive Tract”, SFT - Theriogenology Annual Conference - Portland, 2014. Available at: https://www.ivis.org/library/sft/sft-theriogenology-annual-conference-portland-2014/immunology-and-immunomodulation-of-reproductive-tract (Accessed: 31 May 2023).

    Author(s)

    • morresey

      Morresey P.R.

      BVSc, MVM, MACVSc, DACT, ACVIM, CVA
      Internal Medicine, Rood and Riddle Equine Hospital,
      Read more about this author

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    Provided by:
    Society for Theriogenology

    The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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