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Serum Microrna Profiles in Cycling Mares and Mares With Granulosa Cell Tumors

Author(s):

A.R.G. Lindholm, J.C. da Silveira...

In: SFT - Theriogenology Annual Conference - Milwaukee, 2011 by Society for Theriogenology
Updated:
AUG 13, 2011
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Granulosa cell tumors (GCTs) are the most common ovarian tumor of the horse and can result in suppression of folliculogenesis, stallion-like behavior, and/or continuous estrus. Circulating microRNAs (miRNAs) in women with ovarian cancer are found to change expression patterns in the presence of disease. The objective of our study was to evaluate serum miRNAs expression via quantitative real-time PCR (qRT-PCR) and determine if levels differed in normal cycling mares vs. mares with GCTs. [...]

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The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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