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The Use of Prostaglandin F2α (PGF) for Controlling the Mare's Estrous Cycle

Author(s):
Pinto C.R.
In: SFT - Theriogenology Annual Conference - Louisville, 2013 by Society for Theriogenology
Updated:
AUG 10, 2013
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Introduction
Prostaglandins belong to a group of modified long-chain fatty acids containing 20 carbons called eicosanoids. The cyclooxygenase pathway uses prostaglandin synthases to convert arachidonic acid into prostaglandins. Arachidonic acid is available through the hydrolysis of phospholipids present in the cell membrane. The breakdown of membrane phopholipids is catalyzed by the enzyme phospholipase A. Two isoforms of prostaglandin synthase exist: a constitutive (cyclooxygenase-1) and an inducible (cyclooxygenase-2) isoforms. Systemic administration of prostaglandins (mainly PGF in animals) is associated with side effects affecting the central nervous system (incoordination, stupor and ataxia) and the vascular system (contraction of smooth muscle of organs such as the stomach, intestines and urinary bladder). [...]

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How to reference this publication (Harvard system)?

Pinto, C. R. (2013) “The Use of Prostaglandin F2α (PGF) for Controlling the Mare's Estrous Cycle”, SFT - Theriogenology Annual Conference - Louisville, 2013. Available at: https://www.ivis.org/library/sft/sft-theriogenology-annual-conference-louisville-2013/use-of-prostaglandin-f2α-pgf-for-controlling-mares-estrous-cycle (Accessed: 10 June 2023).

Author(s)

  • Carlos Roberto Pinto

    Pinto C.R.

    Professor
    M.M.V. PhD DACT
    Veterinary Clinical Sciences (VCS), School of Veterinary Medicine, Louisiana State University
    Read more about this author

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The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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