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  4. SFT - Theriogenology Annual Conference - Fort Collins, 2017
  5. A 5 ML Dose PG-600® is Detrimental to Ovarian Function and Pregnancy Rate in Ewes During the Breeding Season
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A 5 ML Dose PG-600® is Detrimental to Ovarian Function and Pregnancy Rate in Ewes During the Breeding Season

Author(s):
Kutzler M.A.
In: SFT - Theriogenology Annual Conference - Fort Collins, 2017 by Society for Theriogenology
Updated:
AUG 05, 2017
Languages:
  • EN
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    PG-600® (Intervet/Merck Animal Health, Madison, NJ) is a single dose injectable product containing equine chorionic gonadotropin (80 IU/ml) and human chorionic gonadotropin (40 IU/ml), which is labeled for estrus induction in swine. This drug is also routinely used off-label for out-of-season estrus induction in sheep. However, at the most common dose administered to ewes (3-5 ml), PG-600® is likely to overstimulate the ovaries, resulting in reduced pregnancy rates. The aim of the current study was to determine if a lower dose of PG-600® would not reduce the pregnancy rate. We hypothesized that the pregnancy rates of ewes treated with a low dose of PG-600® during the breeding season would not be different from controls. Polypay ewes were treated with CIDR inserts (Eazi-Breed™ CIDR, Zoetis, Kalamazoo, MI) for 10 days ...

    Corpus luteum, estradiol, estrus induction, progesterone, sheep

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    How to reference this publication (Harvard system)?

    Kutzler, M. A. (2017) “A 5 ML Dose PG-600® is Detrimental to Ovarian Function and Pregnancy Rate in Ewes During the Breeding Season”, SFT - Theriogenology Annual Conference - Fort Collins, 2017. Available at: https://www.ivis.org/library/sft/sft-theriogenology-annual-conference-fort-collins-2017/a-5-ml-dose-pg-600®-detrimental (Accessed: 03 June 2023).

    Affiliation of the authors at the time of publication

    Department of Animal and Rangeland Sciences, Oregon State University, Corvallis, OR

    Author(s)

    • Michelle Kutzler

      Kutzler M.A.

      Assistant Professor of Theriogenology
      DVM PhD Dipl ACT
      Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University
      Read more about this author

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    Society for Theriogenology

    The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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