Pedigree Analysis and Inherited Canine & Feline Reproductive Diseases

Abstract

As theriogenologists, breeders come to us not only for diagnosis and treatment but also with questions pertaining to the genetic nature of a specific disease. The recent advances in molecular genetics and the availability of genetic maps have made it possible to discover the basis of many genetic diseases in the dog and cat. Over 600 inherited diseases have been described in dogs and about 200 in cats, with more genetic diseases being added each year. This has led to the development and growing need for incorporation of clinical genetics into veterinary practice with the reproductive specialist playing an important role in the detection of potentially new genetic diseases and to provide genetic counselling. To provide assistance to the breeder, we as theriogenologists already appreciate the importance of accurately diagnosing a disease and now need to be able to decipher pedigrees along with historical information that will allow us to suggest a reasonable mode of inheritance for a given disease. [...]