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Induction of Hyperactivation in Stallion Sperm Using 4-amynopyridine

Author(s):

M.F. Galati, L.M. Hunyadi, L.A...

In: SFT - Theriogenology Annual Conference - Baltimore, 2012 by Society for Theriogenology
Updated:
AUG 25, 2012
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Hyperactivation is a change in the pattern of sperm motility required for fertility. Procaine- treated stallion sperm evaluated by computerized-assisted sperm motility analysis (CASA) became hyperactivated as defined by decreases in straight line velocity (VSL) and linearity (LIN), and increases in amplitude of lateral head displacement (ALH) and curvilinear velocity (VCL). This also yielded high rates (60%) of homologous in vitro fertilization (IVF). Because procaine may be toxic to oocytes, alternative hyperactivation-inducing treatments are desirable. [...]

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The Society for Theriogenology is an organization of veterinarians dedicated to animal reproduction, whose mission is to promote standards of excellence in reproductive medicine, to provide outreach and education to veterinarians, and to foster continual improvements in theriogenology.

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