Cutaneous Eosinophilic Granulomas in a Pet Holland Lop Rabbit (Oryctolagus cuniculus)

A 2-year-old male intact pet Holland Lop rabbit (Oryctolagus cuniculus) was presented for routine bilateral orchiectomy at which time two distinct raised, alopecic, non-ulcerated skin masses over the right shoulder and caudal abdomen were observed on physical examination. Complete resection of both masses was attained via excisional biopsies which healed without complication. Histologically, the skin masses were identical and were composed of a mixed cellular dermal infiltrate of primarily eosinophils with macrophages, mast cells, lymphocytes, plasma cells, and heterophils. Based on these findings, a diagnosis of eosinophilic granuloma was made, indicating this rare condition should be considered in rabbits presented with similar lesions. ...