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A mathematical model for the pathogenesis of digital dermatitis in cattle
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The incidence of digital dermatitis (DD) remains high and the aetiology of this multifactorial infectious claw disease has not been clarified completely since the first description in 1974 by Cheli and Mortellaro. Mathematical models on the other hand, are becoming more common in veterinary epidemiology. They are being used to discuss complex dynamics of disease and derived from many disciplines, where complex interactions are observed or postulated to exist.
A deterministic mathematical model is presented for the interaction between host and microorganisms during the pathogenesis of bovine digital dermatitis. This approach is an attempt to extrapolate cellular dynamics during the host-pathogen interaction to describe the different courses of disease observed in the individual cow. A severe and a mild course of disease are ...
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