European Veterinary Conference - Voorjaarsdagen
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The Regenerative Effect of Link N on Degenerated Human Bovine and Canine Intervertebral Disc Cells

Author(s):

L. Laagland

In: EVC - Voorjaarsdagen - The Hague, 2016 by European Veterinary Conference - Voorjaarsdagen
Updated:
APR 15, 2016
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Intervertebral disc (IVD) degeneration is a major medical issue and causes back pain
in both humans and dogs(1). New regenerative treatments are desirable, since current treatments are invasive and expensive(2). Link-N stabilizes proteoglycan interactions and considered to be a promising protein to repair degenerated rabbit IVDs(3), modulate the expression of collagen in human IVD cells(4), and restore the glycosaminoglycan (GAG) and collagen II content in degenerated bovine discs(5).

This study aimed to delineate the regenerative effects of Link-N on degenerated bovine, human and especially canine IVD cells in vitro in order to determine the potential of Link-N for the treatment of IVD degeneration in canine patients. […]

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Affiliation of the authors at the time of publication

Department of Clinical Sciences of Companion Animal, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

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Every spring the European Veterinary Conference Voorjaarsdagen used to organize. Important goals of the Voorjaarsdagen Conference were to build friendships between veterinarians at a national and international level, to enhance the quality and availability of veterinary medicine and surgery, and to foster the exchange of scientific information among veterinarians.  The activities of the European Veterinary Conference have ceased with the last meeting in 2019.

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