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Physiopathologie de l’obésité
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Équilibre énergétique : apport versus dépense
Le maintien d’un poids stable nécessite un équilibre parfait entre les apports et les dépenses énergé- tiques au cours du temps. Malgré des fluctuations importantes de leur consommation alimentaire, les animaux sont capables de maintenir un poids très stable. La régulation à long terme de l’équilibre éner- gétique dépend de la coordination et de l’interprétation de signaux périphériques indiquant le niveau des réserves adipeuses. Les signaux les mieux connus sont la leptine et l’insuline. La régulation à court terme fait intervenir des signaux liés aux repas comme la cholécystokinine (CCK) et le gastrin-related peptide (GRP) (Strader et Woods, 2005). […]
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Affiliation of the authors at the time of publication
1Department of Veterinary Clinical Sciences, University of Liverpool, United Kingdom. 2 Ecole Nationale Véterinaire de Nantes, Unité de Nutrition et Endocrinologie, France.
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