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Insuficiencia pancreática exocrina
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> Introducción
El páncreas exocrino es esencial para la digestión y absorción de los nutrientes. Las células de los aci- nis pancreáticos sintetizan y segregan enzimas digestivas (proteasas, lipasas y amilasas) para degradar las proteínas, los lípidos y los glúcidos. Las células de los canales pancreáticos segregan también bicar- bonato con objeto de mantener el pH óptimo para las funciones de digestión y de absorción, así como el FI, que facilita la absorción de cobalamina.
La insuficiencia pancreática exocrina (IPE) es consecuencia de la reducción de síntesis y secreción de las enzimas digestivas del páncreas. La falta de enzimas digestivas en el duodeno provoca un síndrome de maladigestión y malabsorción del contenido intestinal. Al disponer el páncreas exocrino de una gran reserva funcional, los signos clínicos de maladigestión sólo aparecen cuando se ha perdido por lo menos el 90% de la capacidad secretora. […]
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Affiliation of the authors at the time of publication
1Departement of Veterinary Clinical Sciences, The Royal Veterinary College, United Kingdom. 2Royal Canin Research Center, France.
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