British Equine Veterinary Association
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Abnormal Plasma Neuroactive Progestagen Derivatives in Ill, Neonatal Foals Presented to the Neonatal Intensive Care Unit

Author(s):
Aleman M.,
Pickles K.J.,
Conley A.J.,
Floyd E.F.,
Toth B. and
Madigan J.E.
In: BEVA - Annual Congress - Manchester, 2013 by British Equine Veterinary Association
Updated:
SEP 14, 2013
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Aims: To determine the pregnane profile of foals with neonatal maladjustment syndrome (NMS) and compare it with that of healthy controls and sick, non-NMS foals.

Methods: Thirty-two foals with a clinical diagnosis of NMS, 12 foals with other neonatal disorders and 10 healthy control foals were selected for the study. Heparinised blood samples were collected from each group of foals and pregnane and androgen concentrations were determined using liquid chromatography mass spectrometry at 0, 24 and 48 h of age.

Results: Healthy foals showed a significant decrease in pregnane concentrations over the first 48 h of life (P<0.01). Foals with NMS and sick, non-NMS foals had significantly increased progesterone, pregnenolone, androstenedione dehydroepiandrosterone and epitestosterone concentrations compared with healthy foals (P<0.05). [...]

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How to reference this publication (Harvard system)?

Aleman, M. et al. (2013) “Abnormal Plasma Neuroactive Progestagen Derivatives in Ill, Neonatal Foals Presented to the Neonatal Intensive Care Unit”, BEVA - Annual Congress - Manchester, 2013. Available at: https://www.ivis.org/library/beva/beva-annual-congress-manchester-2013/abnormal-plasma-neuroactive-progestagen-derivatives-ill-neonatal-foals-presented-to-neonatal (Accessed: 07 June 2023).

Author(s)

  • Monica Aleman

    Aleman M.

    Professor
    MVZCert, PhD, Dipl. ACVIM (LAIM & Neurology)
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California
    Read more about this author
  • K.J. Pickles

    Pickles K.J.

    BVMS, MSc, PhD, CertEM(Int Med), DipECEIM
    chine house veterinary hospital ,
    Read more about this author

  • Conley A.J.

    BVSc PhD
    Department of Population Health and Reproduction, School of Veterinary Medicine, University of California
    Read more about this author
  • Emily Haggett - Rossdales Veterinary Surgeons

    Floyd E.F.

    Veterinary Specialist and Partner at Rossdales
    BVSc, DipACVIM, MRCVS
    Rossdales Equine Hospital & Diagnostic Centre,
    Read more about this author
  • Toth Balazs

    Toth B.

    DVM Dipl. ACVIM, MS, MSc
    Equi-Med Kft.,
    Read more about this author
  • John Madigan

    Madigan J.E.

    Professor of Medicine and Epidemiology
    MS DVM Dipl. ACVIM ACAW
    Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California
    Read more about this author

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