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A Prospective Randomised Study to Compare the Effects of Preoperative Hypertonic Saline or Pentastarch on Haematological Variables and Long-term Survival of Surgical Colic Cases

Author(s):

Miller A.J., Barron K.E., Proudman...

In: BEVA - Annual Congress - Manchester, 2013 by British Equine Veterinary Association
Updated:
SEP 14, 2013
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Aims: To compare the effects of hypertonic saline and pentastarch on packed cell volume (PCV) and total protein (TP) immediately preoperatively and on long-term survival of horses undergoing emergency exploratory laparotomy.

Methods: One hundred horses presenting to the Philip Leverhulme Equine Hospital between 2004 and 2008 with signs of abdominal pain and PCV≥45% were recruited. Horses were randomly allocated to receive 4 ml/kg bwt of either hypertonic saline (HS; Vetivex, 7.2%; n = 49) or pentastarch (PS; Haes-Steril, 10%; n = 51) preanaesthesia. Blood samples were collected at presentation and post fluid resuscitation. Horse survival was tracked for 4 years following the final recruited case. [...]

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