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Nonulcerative corneal diseases
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Focal trauma to the cornea can inject microbes and debris into the corneal stroma through small epithelial ulcerative micropunctures. Some stromal abscesses may be secondary to systemic disease. A corneal abscess may develop after epithelial cells adjacent to the epithelial micropuncture divide and migrate over the small traumatic ulcer to encapsulate infectious agents or foreign bodies in the stroma. Epithelial cells are more likely to cover a fungal than a bacterial infection. Re-epithelialisation forms a barrier that protects the bacteria or fungi from topically administered antimicrobial medications. Re-epithelialisation of stromal abscesses interferes with both routine diagnostics and treatment ...
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Affiliation of the authors at the time of publication
Professor Emeritus, University of Florida, and Brookseyes, LLC, Florida, USA.
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