Updates on evidence for PRP/IRAP/polyacrylamide hydrogels

There is a growing volume of experimental evidence to indicate that interleukin-1 (IL-1) is important in the pathogenesis of osteoarthritis and that the prevention of its action has positive outcomes [1]. As with other biological therapies, a more comprehensive understanding of the components of IRAP and ACS products is still needed [2,3]. There is little published research into the clinical efficacy of these products in the equine or human literature in naturally occurring disease. The single equine placebo-controlled experimental study in a carpal chip model of early osteoarthritis demonstrated a significant positive outcome in clinical variables ...