Treatment of equine glandular disease beyond omeprazole

It is now widely accepted that disease of the squamous and glandular regions are not the same, regarding either the pathophysiology or epidemiology and natural history. The structure of these two regions are different and the glandular region is designed to thrive in an acidic environment. Reduced gastrointestinal blood flow is likely to play a role in the pathophysiology of this disease and as such pharmacological agents that manipulate this may play a role in treatment. There is some evidence from a histopathological study that disease of the glandular region is inflammatory in origin and may be an extension of inflammatory bowel disease and as such anti-inflammatory medication may be appropriate in these cases. Although this disease manifests as lesions surrounding the pyloric antrum, histopathological changes can often be identified throughout the glandular region ...