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Diagnosis and Treatment of PPID and Metabolic Syndrome
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Diagnosis of pituitary pars intermedia dysfunction
A diagnosis of PPID is based on:
Signalment
The average age is 19 years and horses <10 years are rarely affected. There is no breed or sex predilection, but ponies are more likely to be affected than horses.
Clinical signs
Hirsuitism is the commonest clinical sign, occurring in 55–80% of affected animals. Weight loss is seen in up to 90% of cases. Lethargy, hyperhidrosis, recurrent laminitis, increased susceptibility to infections and polyuria/polydipsia also occur.
Further diagnostic tests
Haematology may be normal or may reveal a stress leucogram. Biochemistry may be normal or may reveal hyperglycaemia and/or increased liver enzymes. However, these alterations are nonspecific. Hormone assays include measurement of: [...]
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