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Identification of genes of interest for the treatment of heavesaffected horses
E. Ramery, R. Closset, E. Salinas...
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La pousse ou l'obstruction récurrente des voies respiratoires est une des causes les plus fréquentes de pathologie pulmonaire chronique chez le cheval. Elle se caractérise par une inflammation et une obstruction des petites voies respiratoires en réponse à l’inhalation de poussières organiques incluant moisissures et endotoxines présentes dans le foin et la paille. Il est essentiel de comprendre la pathophysiologie de la pousse afin de pouvoir développer des traitements plus efficaces. Grâce à l’utilisation des micro-damiers, il est possible de tester rapidement et simultanément l’expression de milliers de gènes. Grâce à un micro-damier hétérologue (Affymetrix GeneChip Human Genome Array ), l’expression génomique de plus de 23.000 gènes a été étudiée dans les cellules ...
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Affiliation of the authors at the time of publication
Département des sciences fonctionnelles, Faculté de médecine vétérinaire, Université de Liège, 20 Boulevard de Colonster, B-4000 Liège
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