American Academy of Veterinary Pharmacology and Therapeutics
Back to Table of Contents
Add to My Library
Comments
Share:

Antimicrobial Susceptibility Testing: Breakpoint Setting History and Perspective

Author(s):
Papich M.G.
In: AAVPT - Biennial Symposium - Overland Park, 2019 by American Academy of Veterinary Pharmacology & Therapeutics
Updated:
AUG 23, 2019
Languages:
Back to Table of Contents
Add to My Library

Introduction
The Clinical and Laboratory Standards Institute (CLSI) Veterinary Antimicrobial Susceptibility Testing (VAST) subcommittee has been active since 1993. Before VAST started developing veterinary-specific breakpoints, all susceptibility testing for bacteria isolated from animals used the human standards (M100). Testing standards for bacteria isolated from animals were needed to provide the best guidance for drug selection, interpretation, and monitoring programs. The latest edition of the published standard is the 5th edition (CLSI VET01, 2018). The accompanying document published as a supplement (VET08) has tables with antimicrobial agents recommended for testing, interpretive categories and breakpoints, and quality control (QC) ranges. The most recent version is in its 4th edition (CLSI VET08, 2018). The VAST subcommittee has developed breakpoints for 186 drug-bug combinations. Since 2015, there have been 41 new breakpoints with 34 of these developed by the Generic Drug Working Group (described below). [...]

View full text
Back to Table of Contents
Add to My Library

Ask the author

0 comments
Submit

How to reference this publication (Harvard system)?

Papich, M. G. (2020) “Antimicrobial Susceptibility Testing: Breakpoint Setting History and Perspective”, AAVPT - Biennial Symposium - Overland Park, 2019. Available at: https://www.ivis.org/library/aavpt/aavpt-biennial-symposium-overland-park-2019/antimicrobial-susceptibility-testing-breakpoint-setting-history-and-perspective (Accessed: 06 December 2023).

Author(s)

  • Papich M.G.

    Professor of Clinical Pharmacology
    DVM MS PhD Dipl ACVCP
    College of Veterinary Medicine, North Carolina State University
    Read more about this author

Copyright Statement

© All text and images in this publication are copyright protected and cannot be reproduced or copied in any way.

Readers also viewed these publications

Provided by:

The purpose of the Academy is promotion of the science of veterinary pharmacology and therapeutics. The AAVPT was founded in 1977 and consists of a diverse membership of almost 300 from over 20 countries. The membership shares a common interest in research and teaching in veterinary pharmacology. Membership in the AAVPT - be it as a Student Member, Associate Fellow, or Fellow - is open to individuals with background and training in veterinary pharmacology.

Learn more
Back To Top