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Ocular Findings in Quarter Horses with Hereditary Equine Regional Dermal Asthenia
C.A. Mochal, W.W. Miller, A.J...
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1. Introduction
Hereditary equine regional dermal asthenia (HERDA) is caused by a missense mutation in the equine cyclophilin B gene, which may also affect tissues other than the horse’s skin. Ocular structures of Quarter Horses homozygous (Hr/Hr) for HERDA were therefore compared with those of nonHERDA (N/N) Quarter Horses.
2. Materials and Methods
This was a prospective study that evaluated the ocular structures in 10 HERDA and 10 non-HERDA horses. Ophthalmic examination, Schirmer tear tests, tonometry, cornea pachymetry, histopathology and scanning electron microscopy were performed on these animals. A retrospective study was also conducted on 28 HERDA horses and 291 non-HERDA horses. Records were reviewed to compare the incidence of corneal ulceration in HERDA and non-HERDA horses over a 4-yr period. [...]
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About
Affiliation of the authors at the time of publication
Department of Clinical Sciences (Mochal, Miller, Linford, Rashmir-Raven) and Department of Pathobiology and Population Medicine (Cooley, Ryan), College of Veterinary Medicine, Mississippi State University, PO Box 6100, Mississippi State, Mississippi 39762, USA
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