AAEP Annual Convention Las Vegas 2009
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Equine Encephalomyelitis Outbreak Caused by a Genetic Lineage 2 West Nile Virus in Hungary

Author(s):

O. Kutasi, I. Biksi, T. Bakonyi, E...

In: AAEP Annual Convention - Las Vegas, 2009 by American Association of Equine Practitioners
Updated:
DEC 09, 2009
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1. Introduction
The aim of the present study is to describe the results of clinical and virological investigations on the first outbreak of a genetic lineage 2 West Nile virus (WNV) encephalomyelitis in horses.

2. Materials and Methods
Data were collected from 18 horses showing nervous system symptoms between August and October 2008. Diagnosis was based on serologic testing. Histopathology was carried out on four horses, two of which were assessed for the presence of WNV in their nervous system.

3. Results
Neutralizing antibody titers were between 10 and 270 (median= 94 ± 72) 2–35 days after the onset of clinical signs. The results of other serological assays were concordant with the plaque reduction neutralization test (PRNT). Common signs were ataxia, weakness, asymmetric gait, muscle tremors, hypersensitivity, cranial nerve deficits, and recumbency. Thirteen animals survived. Both tested specimens were positive and allowed for molecular characterization of the viral strain. [...]

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Affiliation of the authors at the time of publication

Large Animal Clinic, Ullo, Dora Major 2225, Szent Istvan University, Faculty of Veterinary Science, Hungary

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