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Clinical Follow-Up of Horses Treated with Bone Marrow - Derived Mesenchymal Stem Cells for Musculoskeletal Lesions
D.J. Ferris, D.D. Frisbie, J.D...
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1. Introduction
Bone marrow– derived mesenchymal stem cells (BMSCs) have garnered increasing attention as a viable therapy for musculoskeletal lesions in horses, humans, and other animals. Clinical follow-up information has been limited mainly to case reports with low numbers. The goal of this study was to provide follow-up information on a modest number of horses suffering musculoskeletal lesions treated with BMSCs.
2. Materials and Methods
Horses (n = 162) receiving BMSCs expanded at Colorado State University’s Orthopaedic Research Laboratory (ORC), or Advanced Regenerative Therapies (ART) were retrospectively followed based on medical record analysis and follow-up interview with the attending veterinarian/owner. Six separate centers participated. [...]
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Affiliation of the authors at the time of publication
Gail Holmes Equine Orthopaedic Research Center, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA (Ferris, Frisbie, Kisiday, McIlwraith, Kawcak, Goodrich); Oakridge Equine Hospital PC, 6675 East Waterloo Road, Edmond, Oklahoma 73034, USA (Hague, Major, Zubrod); Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington 99164 (Schneider); Veterinary Medical Teaching Hospital, Texas A&M University, College Station, Texas 77843, USA (Watkins)
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