AAEP Annual Convention Las Vegas 2009
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Chemoprophylactic Effects of Gallium Maltolate Against Rhodococcus equi Pneumonia Among Foals at Endemic Equine Breeding Farms

Author(s):
Chaffin M.K.,
Cohen N.D.,
Martens R.J.,
O'Conor M.S. and
Bernstein L.R.
In: AAEP Annual Convention - Las Vegas, 2009 by American Association of Equine Practitioners
Updated:
DEC 09, 2009
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1. Introduction
Rhodococcus equi causes severe pneumonia in foals worldwide. Most affected foals likely become infected early in life. We previously reported the results of a clinical trial showing that chemoprophylaxis with azithromycin reduced the incidence of R. equi pneumonia. This preventative strategy has limited practical application because of the potential for development of antimicrobial resistance. Gallium maltolate (GaM) has shown potential for control of R. equi pneumonia. The objective of this study was to determine the effects of GaM chemoprophylaxis on the incidence of R. equi pneumonia among foals at R. equi-endemic equine breeding farms.

2. Materials and Methods
A controlled, randomized, double-blind clinical trial was performed at 12 equine breeding farms with histories of endemic R. equi infections. Foals assigned to group 1 were treated with a placebo (indistinguishable from GaM formulation) during the first 2 wk of life, and foals assigned to group 2 were treated with GaM formulation (~30 mg/kg, q 24 h, PO) during the first 2 wk of life. Enrolled foals were monitored for development of R. equi pneumonia. Data were compared between treatment groups. [...]

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How to reference this publication (Harvard system)?

Chaffin, M. et al. (2009) “Chemoprophylactic Effects of Gallium Maltolate Against Rhodococcus equi Pneumonia Among Foals at Endemic Equine Breeding Farms”, AAEP Annual Convention - Las Vegas, 2009. Available at: https://www.ivis.org/library/aaep/aaep-annual-convention-las-vegas-2009/chemoprophylactic-effects-of-gallium-maltolate-against-rhodococcus-equi-pneumonia-among-foals-at (Accessed: 28 November 2023).

Author(s)

  • Chaffin M.K.

    DVM MS
    Department of Large Animal Medicine and Surgery, College of Vet. Medicine & Biomedical Sciences, Texas A & M University
    Read more about this author

  • Cohen N.D.

    Associate Professor of Medicine
    VMD MPH PhD Dipl ACVIM
    Equine Infectious Disease Laboratory, Department of Large Animal Clinical Sciences, College of Vet. Medicine & Biomedical Sciences, Texas A & M University
    Read more about this author

  • Martens R.J.

    DVM
    Equine Infectious Disease Laboratory, Department of Large Animal Clinical Sciences, College of Vet. Medicine & Biomedical Sciences, Texas A & M University
    Read more about this author

  • O'Conor M.S.

    BS MS
    Department of Large Animal Medicine and Surgery, College of Vet. Medicine & Biomedical Sciences, Texas A & M University
    Read more about this author

  • Bernstein L.R.

    PhD
    Terrametrix,
    Read more about this author

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