Gustafson D.L.

Dr. Gustafson is a professor of cancer pharmacology and director of the pharmacology core. He also holds the Shipley University Chair in Comparative Oncology. The Gustafson laboratory focuses on developing therapeutic treatment modalities for cancer with an emphasis on the pharmacology of agents and development of animal, pharmacokinetic, and mathematical model systems that better reflect the clinical progression and pathology of cancer. Current projects include mechanism of action and pharmacology of the MEK inhibitor AZD6244 in human melanoma cell lines and tumor xenografts in mouse models alone and in combination with cytotoxic chemotherapy; drug combinations that target stromal and cancer cells; and pharmacokinetic modeling to describe, simulate and predict effects.