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In:  Clinical Neurology in Small Animals - Localization, Diagnosis and Treatment.  K. G. Braund (Ed.)

Publisher:  International Veterinary Information Service, Ithaca, New York, USA.

Epilepsy
M. Berendt

References

 
1.  Jackson JH. Selected writings of John Hughlings Jackson. In: Tailor J (Ed.). Epilepsy & Epileptiform convulsions. vol. 1. London: Hodder and Stroughton, 1931, pp. 500.
 
2.  Berger H. Über das Electroencephalogram des Mennschen. Arch Psychiat 1929; 87: 527-570.
 
3.  Pallaske G. Hirnbefunde bei 2 Hunden mit klinisch typischer Epilepsie. Arch Tierheilk 1935; 69:43-45.
 
4.  Frauchiger E, Frankhauser R. Die Nervekrankheiten unsere Hunde. Medicinisher Verlag, Hans Huber Bern, 1949; 161-180.
 
5.  Croft PG. The EEG as an aid to diagnoses of nervous diseases in the dog and cat. J Small Anim Pract 1964; 5:540-541.
 
6.  Redding RW. A simple technique for obtaining an electroencephalogram of the dog. Am J Vet Res 1964; 25:854-857.
 
7.  Klemm WR. Technical aspects of electroencephalography in animal research. Am J Vet Res 1965; 26:1237-1248.
 
8.  Holliday TA, Cunningham JG, Gutnick MJ. Comparative clinical and electroencephalographic studies of canine epilepsy. Epilepsia 1970; 11:281.
 
9.  Holliday TA. Seizure disorders. Vet Clin North Am (Small Anim Pract) 1980; 10:3-29.
 
10.  Holliday TA, Williams DC. Interictal paroxysmal discharges in the electroencephalograms of epileptic dogs. Clin Tech Small Anim Pract 1998; 13:132-143. - PubMed -
 
11.  Klemm WR. Electroencephalography in the diagnosis of epilepsy. Probl Vet Med 1989; 1:535-556. - PubMed -
 
12.  Srenk P, Jaggy A. Interictal electroencephalographic findings in a family of Golden Retrievers with idiopathic epilepsy. J Small Anim Pract 1996; 37:317-321. - PubMed -
 
13.  Jaggy A, Bernadini M. Idiopathic epilepsy in 125 dogs: a long-term study. Clinical and electroencephalographic findings. J small Anim Pract 1998; 39:23-29. - PubMed -
 
14.  Berendt M, Høgenhaven H, Flagstad A, et al. Electroencephalography in dogs with epilepsy: Similarities between human and canine findings. Acta Neurol Scand 1999; 99:276-283. - PubMed -
 
15.  Morita T, Shimada A, Takeuchi T, et al. Cliniconeuropathologic findings of familial frontal lobe epilepsy in Shetland sheepdogs. Can J Vet Res 2002; :35-41. - PubMed -
 
16.  Commission on epidemiology and prognosis, International League Against Epilepsy. Guidelines on epidemiology and prognosis, International League Against Epilepsy. Epilepsia 1993; 34:592-596.
 
17.  Koestner A, Rehfeld CE. Idiopathic Epilepsy in a Beagle Colony. ANL - 7535. ANL Rep 1968; 178-179.
 
18.  Bielfelt SW, Redman HC, McClellan RO. Sire- and sex-related differences in rates of epileptiform seizures in a purebred Beagle dog colony. Am J Vet Res 1971; 32:2039-2048.
 
19.  Löscher W, Meldrum BS. Evaluation of anticonvulsant drugs in genetic animal models of epilepsy. Fed Proc 1984; 43:276-284.
 
20.  Schwartz-Porsche D. Seizures. In: Braund KG, ed. Clinical syndromes in veterinary neurology. 2nd ed. Missouri: Mosby, 1994; 238-251. - Available from amazon.com -
 
21.  Jaggy A, Faissler D, Gaillard C, et al. Genetic aspects of idiopathic epilepsy in Labrador Retrievers. J Small Anim Pract 1998; 39:275-280. - PubMed -
 
22.  Srenk P, Jaggy A, Gaillard C, et al. Genetische Grundlagen der idiopathischen Epilepsie beim Golden Retriever. Tierärtl Prax 1994; 22:574-578.
 
23.  Heynold Y, Faissler D, Steffen F, et al. Clinical, epidemiological and treatment results of idiopathic epilepsy in 54 Labrador Retrievers: a long-term study. J small Anim Pract 1997; 38:7-14. - PubMed -
 
24.  SAS Procedures Guide, Version 6, 3rd ed. Cary: SAS Institute Inc., 1990; 705. - Available from amazon.com -
 
25.  Berendt M, Gredal H, Pedersen LG, et al. A Cross-sectional study of epilepsy in Danish Labrador Retrievers: Prevalence and selected risk factors. J Vet Int Med 2002; 16: 262-268. - PubMed -
 
26.  Van der Velden NA. Fits in Tervueren shepherd dogs: A presumed hereditary trait. J Small Anim Pract 1968; 9;63-70.
 
27.  Farnbach GC. Seizures in dogs. Part 1. Basis, classification, and predilection. Compend Contin Educ Pract Vet 1984; 6;569-574.
 
28.  Podell M, Fenner WR, Powers JD. Seizure classification in dogs from a nonreferral-based population. J Am Vet Med Assoc 1995; 11:1721-1728. - PubMed -
 
29.  Berendt M, Gram L. Epilepsy and seizure classification in 63 dogs: A reappraisal of veterinary epilepsy terminology. J Vet Int Med 1999; 13:14-20. - PubMed -
 
30.  Placencia M, Sander JWAS, Roman M, et al. The characteristics of epilepsy in a largely untreated population in rural Ecuador. J Neurol Neurosurg Psychiatry 1994; 57:320-325. - PubMed -
 
31.  Sander JWAS, Sillanpää M. Natural history and prognosis. In: Engel J, Pedley TA, eds. Epilepsy: A Comprehensive Textbook. Philadelphia: Lippencott-Raven Publishers; 1997; 69-86. - Available from amazon.com -
 
32.  Quesnel AD, Parent JM, McDonell W. Clinical management and outcome of cats with seizure disorders: 30 cases (1991-1993). J Am Vet Med Assoc 1997; 210:72-77. - PubMed -
 
33.  Sander JWAS, Shorvon SD. Incidence and prevalence studies in epilepsy and their methodological problems: a review. J Neuro Neurosurg Phychiat 1987; 50:829-839. - PubMed -
 
34.  Hauser WA. Recent developments in the epidemiology of epilepsy. Acta Neurol Scand 1995; (suppl 162):17-21. - PubMed -
 
35.  Fisher RS. Cellular mechanisms of the epilepsies. In: Hopkins A, Shorvon S, Cascino G eds. Epilepsy. London: Chapman & Hall, 1995; 35-58. - Available from amazon.com -
 
36.  Johnston MV. Neurotransmitters and epilepsy. In: Elaine Wyllie ed. The treatment of epilepsy: Principles and practice. 2nd ed. Baltimore: Williams & Wilkins, 1996; 122-138. - Available from amazon.com -
 
37.  Macdonald RL, In: Engel J & Pedley TA eds. Epilepsy: A comprehensive textbook. Philadelphia: Lippincott-Raven Publishers, 1997; 265-275. - Available from amazon.com -
 
38.  Podell M, Hadjiconstantinou M. Cerebrospinal fluid gamma-aminobutyric acid and glutamate values in dogs with epilepsy. Am J Vet Res 1997;58:451-456. - PubMed -
 
39.  March PA. Seizures: Classification, etiologies, and patophysiology. Clin Tech Small Anim Pract 1998; 13:119-131. - PubMed -
 
40.  Herzog AG. Reproductive endocrine considerations and hormonal therapy for women with epilepsy. Epilepsia 1991; 32(suppl.6):S27-S33. - PubMed -
 
41.  Hopkins A. Epilepsy, mestruation, oral contraception and pregnancy. In: Hopkins A, Shorvon S, Cascino G eds. Epilepsy. London: Chapman & Hall 1995; 521-533. - Available from amazon.com -
 
42.  Herkes GK, Eadie MJ, Sharbrough F, Moyer T. Patterns of seizure occurrence in catamenial epilepsy. Epilepsy Res 1993; 15:47-52. - PubMed -
 
43.  Rosciszewska D, Buntner B, Guz I et al. Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual cycle in women with epilepsy. J Neurol Neurosurg Psychiat 1986; 49:47-51. - PubMed -
 
44.  Wallace ME. Keeshonds: A genetic study of epilepsy and EEG readings. J Small Anim Pract 1975;16:1-10.
 
45.  Cunningham JG, Farnbach GC. Inheritance and idiopathic epilepsy. J Am Anim Hosp Assoc 1988; 24:421-424.
 
46.  Hall SJG, Wallace ME. Canine epilepsy: A genetic counselling programme for Keeshonds. Vet Rec 1996; 138:358-360. - PubMed -
 
47.  Kathmann I, Jaggy A, Busato A, et al. Clinical and genetic investigations of idiopathic epilepsy in the Bernese Mountain Dog. J Small Anim Pract 1999; 40:319-325. - PubMed -
 
48.  Famula TR, Oberbauer AM. Segregation analysis of epilepsy in the Belgian Tervueren dog. Vet Rec 2000; 147:218-221. - PubMed -
 
49.  Wilson JV, Reynolds EH. Translation and analysis of a cuneiform text forming part of a Babylonian treatise on epilepsy. Medical History 1990; 34:185-198.
 
50.  Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 1981; 22:489-501.
 
51.  Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30:389-399.
 
52.  Loiseau P. Idiopathic and benign partial epilepsies of childhood. In: Elaine Wyllie ed. The treatment of epilepsy: Principles and practice. 2nd ed. Baltimore: Williams & Wilkins, 1996; 442-450. - Available from amazon.com -
 
53.  Berkovic SF, McIntosh A, Howell R, et al. Familial temporal lobe epilepsy: A common disorder identified in twins. Ann Neurol 1996;40:227-235. - PubMed -
 
54.  Thomas WB, Schueler RO, Kornegay JN. Surgical exicion of a cerebral arteriovenous malformation in a dog. Progress Vet Neurol 1995; 6:20-23.
 
55.  Raymond AA, Fish DR, Sisodiya SM et al. Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy. Brain 1995;118:629-660. - PubMed -
 
56.  Summers BA, Cummings JF, deLahunta A. Veterinary Neuropathology. Missoury: Mosby 1995; 244-246. - Available from amazon.com -
 
57.  Quesnel AD, Parent JM, McDonell W, et al. Diagnostic evaluation of cats with seizure disorders: 30 cases (1991-1993). J Am Vet Med Assoc 1997; 210:65-71. - PubMed -
 
58.  Bagley RS, Gavin PR. Seizures as a complication of brain tumors in dogs. Clin Technich Small Anim Pract 1998; 13:179-184. - PubMed -
 
59.  Bush W, Darrin E, Shofer F, et al. Age, neurological examination and cerebrospinal fluid analysis as predictors of outcom of MRI scanning in 115 dogs with seizures. Proceedings, 19th Annual ACVIM Forum, J Vet Int Med 2001; 15: 317.
 
60.  Kipar A, Hetzel U, Aarmien AG, et al. Bilateral focal cerebral angiomatosis associated with nervous signs in a cat. Vet Pathol 2001; 38:350-353. - PubMed -
 
61.  Kaiser E, Krauser K, Schwartz-Porsche D. Lafora-Erkrankung (progressive Myoklonusepilepsie) beim Bassethund – Möglichkeit der Früherkennung mittels Muskelbiopsie? Vergleich der Einschlusskörperchen in Hirn und Muskel, dargestellt an zwei ausgewerteten Fällen. Tierärztl Praxis 1991; 19:290-295.
 
62.  Gredal H, Berendt M, Leifsson PS. Progressive myoclonus epilepsy in a beagle. J Small Anim Pract 2003; 44:511-514. - PubMed -
 
63.  Taylor DC, Falconer MA, Bruton CJ, et al. Focal dysplasia of the cerebral cortex in epilepsy. J Neurol Neurosurg Psychiat 1971; 34:369-387.
 
64.  Palmini A, Andermann F, Olivier A, et al. Focal neuronal migration disorders and intractable epilepsy: a study of 30 patients. Ann Neurol 1991; 30:741-749. - PubMed -
 
65.  Kuzniecky R, Garcia J, Faught E, et al. Cortical dysplasia in temporal lobe epilepsy: magnetic resonance imaging correlations. Ann Neurol 1991; 29:293-298. - PubMed -
 
66.  Raymond AA, Fish DR, Sisodiya SM et al. Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy. Brain 1995; 118:629-660. - PubMed -
 
67.  King MA, Newton MR, Fitt GJ et al. Epileptology of the first seizure: Study of 200 consecutive cases. Epilepsia 1996; 37(suppl.-5):82.
 
68.  Buckmaster PS, Smith MO, Buckmaster CL, et al. Absence of Temporal lobe epilepsy pathology in dogs with medically intractable epilepsy. J Vet Int Med 2002; 16:95-99. - PubMed -
 
69.  Montgomery DL, Lee AC. Brain damage in the epileptic beagle dog. Vet Pathol 1983;20:160-169. - PubMed -
 
70.  Fatzer R, Gandini G, Jaggy A, et al. Necrosis of hippocampus and piriform lobe in 38 domestic cats with seizures: A retrospective study on clinical and pathological findings. J Vet Int Med 2000; 14:100-104. - PubMed -
 
71.  Morita T, Shimada A, Ohama E et al. Oligodendroglial vacuolar degeneration in the bilateral motor cortices and astrocytosis in epileptic beagle dogs. J Vet Med Sci 1999; 61:107-111. - PubMed -
 
72.  Mellema LM, Koblik PD, Kortz GD, et al. Reversible magnetic resonance imaging abnormalities in dogs following seizures. Vet Radiol Ultrasound 1999; 40:588-595. - PubMed -
 
73.  Sabers A, Alving J, Gram L. Evaluation of the Danish Epilepsy Center: Adults. Seizure 1992; 1(suppl A):P13/34.
 
74.  Bell WL, Walczak TS, Shin C, et al. Painfull generalized clonic and tonic-clonic seizures with retained consciousness. J Neurol Neurosurg Psychiat 1997;63:792-795. - PubMed -
 
75.  Berendt M, Gredal H, Alving A. Characteristics and phenomenology of epileptic partial seizures: A retrospective study of 70 dogs (1995-2000). Submitted 2002.
 
76.  Dreifuss FE. Classification of epileptic seizures. In: Engel J, Pedley TA eds. Epilepsy. A comprehensive textbook. Philadelphia: Lippincott-Raven Publishers, 1998; 517-524. - Available from amazon.com -
 
77.  Raw ME, Gaskell CJ. A review of one hundred cases of presumed canine epilepsy. J Small Anim Pract 1985; 26:645-652.
 
78.  Holland CT. Succesfull long term treatment of a dog with psychomotor seizures using carbamazepine (temporal lobe epilepsy; case report). Aust Vet J 1988; 65:389-392. - PubMed -
 
79.  Dodman NH, Miczek KA, Knowles K, et al. Phenobarbital-responsive episodic dyscontrol (rage) in dogs. J Am Vet Med Assoc 1992; 201:1580-1583. - PubMed -
 
80.  Dodman NH, Knowles KE, Shuster L, et al. Behavioural changes associated with suspected complex partial seizures in Bull Terriers. J Am Vet Med Assoc 1996; 208:668-691.
 
81.  Sorde A, Pumarola M, Fondevila MD, et al. Psychomotor epilepsy associated with metastatic thymoma in a dog. J Small Anim Pract 1994; 35:377-380.
 
82.  Panayiotopoulos CP. Vomiting as an ictal manifestation of epileptic seizures and syndromes. J Neurol Neurosurg Psychiat 1988; 51:1448-1451. - PubMed -
 
83.  Colter SB. Complex partial seizures. Behavioural epilepsy. Prob Vet Med 1989; 1:619-627. - PubMed -
 
84.  Cromwell-Davis SL, Lappin M, Oliver JE. Stimulus responsive psychomotor epilepsy in a Doberman Pinscher. J Am Anim Hosp Assoc 1989; 25:57-60.
 
85.  Stonehewer J, Mackin AJ, Tasker S, et al. Idiopathic phenobarbital-responsive hypersialosis in the dog: An unusual form of limbic epilepsy? J Small Anim Pract 2000; 41:416-421. - PubMed -
 
86.  Lüders HO, Burgess R, Noachtar S. Expanding the international classification of seizures to provide localization information. Neurology 1993; 43:1650-1655.
 
87.  Lüders H, Acharya J, Baumgartner, et al. Semiological seizure classification. Epilepsia 1998; 39:1006-1013. - PubMed -
 
88.  Engel J. Classification of the international league against epilepsy: Time for reappraisal. Epilepsia 1998; 39:1014-1017.
 
89.  Parent JM. Clinical managemant of canine seizures. Vet Clin North Am (Small Anim Pract) 1988; 18:947-963. - PubMed -
 
90.  LeCouteur RA, Child G. Clinical management of epilepsy of dogs and cats. Probl Vet Med 1989; 1:578-595. - PubMed -
 
91.  Shell LG. The differential diagnoses of seizures. Symposium on seizure disorders. Vet Med 1993; 88:629-640.
 
92.  Jadhav KM, Gnanaprakasam V. A study on metabolic causes of convulsive episodes in canines. Cheiron 2000; 29:166-168.
 
93.  Placencia M, Shorvon S, Paredes V, et al. Epileptic seizures in an Andean region in equador: incidence and prevalence and regional variation. Brain 1992; 115:771-782. - PubMed -
 
94.  Cockrell OC, Johnson AL, Sander JWAS et al. Prognosis of epilepsy: a review and further analysis of the first nine years of the British National General Practice Study of epilepsy, a prospective population based study. Epilepsia;1997; 38:31-46. - PubMed -
 
95.  Sabers A, Gram L. Newer anticonvulsants. Comparative review of drug interactions and adverse effects. Drugs 2000; 60:23-33. - PubMed -
 
96.  Frey HH. Anticonvulsant drugs used in the treatment of epilepsy. Probl Vet Med 1989; 1:558-577. - PubMed -
 
97.  Speziale J, Dayrell-Hart B, Steinberg SA. Clinical evaluation of gamma-vinyl-gamma-aminobutyric acid for control of epilepsy in dogs. J Am Vet Med Assoc 1991; 198:995-1000. - PubMed -
 
98.  Schroeder CE, Gibson JP, Yarrington J, et al. Effects of high-dose-vinyl GABA (vigabatrin) administration on visual and somatosensory evoked potentials in dogs. Epilepsia 1992; 33 (suppl. 5):S13-25. - PubMed -
 
99.  Dyer KR, Shell LG. Anticonvulsant therapy: a practical guide to medical management of epilepsy in pets. Vet Med 1993; 88:647-653.
 
100.  Schnict S, Wigger D, Frey HH. Pharmacokinetics of oxcarbazepine in the dog. J Vet Pharmacol Therapheutics 1996; 19:27-31. - PubMed -
 
101.  O’Brien DP, Simpson ST, Longshore RC et al. Nimodipine for treatment of idiopathic epilepsy in dogs. J Am Vet Med Assic 1997; 210:1298-1301. - PubMed -
 
102.  Podell M. Antiepileptic drug therapy. Clin Techniq Small Anim Pract 1998; 13:185-192. - PubMed -
 
103.  Ruehlmann D, Podell M, March P. Treatment of partial seizures and seizure-like activity with felbamate in six dogs. J Small Anim Pract 2001; 42:403-408. - PubMed -
 
104.  Frey HH, Göbel W, Lösher W. Pharmacokinetics of primidone and its active matabolites in the dog. Arch Int Pharmacodyn 1979; 242:14-30. - PubMed -
 
105.  Al-Tahan F, Frey HH. Absorption kinetics and bioavailability of phenobarbital after oral administration to dogs. J Vet Pharmacol Ther 1985; 8:205-207.
 
106.  Cochrane SM, Black WD, Parent JM, et al. Pharmacokinetics of Phenobarbital in the cat following intravenous and oral administration. Can J Vet Res 1990; 54:132-138. - PubMed -
 
107.  Cochrane SM, Parent JM, Black WD, et al. Pharmacokinetics of phenobarbital in the cat following multiple oral administration. Can J Vet Res 1990; 54:309-312. - PubMed -
 
108.  Johnston MV. The treatment of epilepsy. In: Elaine Wyllie ed. The Treatment of Epilepsy: Principles and practice. 2nd ed. Baltimore: Williams & Wilkins, 1996; 122-138. - Available from amazon.com -
 
109.  Lösher W. A comparative study of the protein binding of anticonvulsant drugs in serum of dog and man. J Pharmacol Exp Ther 1979; 208:429-435.
 
110.  Gieger TL, Hosgood G, Taboada J, et al. Thyroid function and serum hepatic enzyme activity in dogs after phenobarbital administration. J Vet Int Med 2000; 14:277-281. - PubMed -
 
111.  Rambeck B, May TW, Jürgens U, et al. Phenobarbital-konzentrationen bei anfallskranken hunden unter phenobarbital - oder primidon.therapie. Kleintierpraxis 1999; 44:345-354.
 
112.  Levitski RE, Trepanier LA. Effect of timing of blood collection on serum phenobarbital concentrations in dogs with epilepsy. J Am Vet Med Assoc 2000; 217:200-204. - PubMed -
 
113.  Dayrell-Hart B, Steinberg SA, Van winkle, et al. Hepatotoxicity of phenobarbital in dogs: 18 cases (1985-1989). J Am Vet Med Assoc 1991; 199:1060-1066. - PubMed -
 
114.  Ernst JP, Doose H, Baier WK. Bromide were effective in intractable epilepsy with generalized tonic-clonic seizures and onset in early childhood. Brain Develop 1988; 10:385-388. - PubMed -
 
115.  Schwartz-Porsche D, Jürgens U. Wirksamheit von bromid bei den therapieresistent epilepsien des hundes. (Effectiveness of bromide in therapy resistant epilepsy of dogs). Tiearztl Prax 1991; 19;395-401. - PubMed -
 
116.  Podell M, Fenner WR. Bromide therapy in refractory canine idiopathic epilepsy. J Vet Int Med 1993; 7:318-327. - PubMed -
 
117.  Uthman BS, Beydoun A. Less commonly used antiepileptic therapies. In: Elaine Wyllie ed. The Treatment of Epilepsy: Principles and practice. 2nd ed. Baltimore: Williams & Wilkins, 1996; 937-953. - Available from amazon.com -
 
118.  Shaw N, Trepanier LA, Center SA, et al. High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog. J Am Vet Med Assoc 1996; 208:234-236. - PubMed -
 
119.  Yohn SE, Wallace BM, Sharp PE. Bromide toxicosi (bromism) in a dog treated with potassium bromide for refractory seizures. J Am Vet Med Assoc 1992; 201:468-470. - PubMed -
 
120.  Nichols ES, Trepanier LA, Linn K. Bromide toxicosis secondary to renal insufficiency in an epileptic dog. J Am Vet Med Assoc 1996; 208:231-233. - PubMed -
 
121.  Sawchuck SA, Parker AJ, Neff-Davis C, et al. Primidone in the cat. J Am Anim Hosp Assoc 1985; 21:647-650.
 
122.  Bunch SE, Castlemann WL, Hornbuckle WE, et al. Hepatic cirrhosis associated with long-term anticonvulsant drug therapy in dogs. J Am Vet Med Assoc 1982; 181:357-362. - PubMed -
 
123.  Bunch SE, Castlemann WL, Baldwin BH, et al. Effects of long-term primidone and phenytoin administration on canine hepatic function and morphology. Am J Vet Res 1985; 46:105-115. - PubMed -
 
124.  Farnbach GC. Serum concentrations and efficacy of phenytoin, phenobarbital, and primidone in canine epilepsy. J Am Vet Med Assoc 1984; 184:1117-1120. - PubMed -
 
125.  Hassel TM, Mcguire JH, Cooper CG, et al. Phenytoin metabolism in the cat after long-term oral administration. Epilepsia 1984; 25:556-563. - PubMed -
 
126.  Center S, Elston TE, Rowland PH, et al. Hepatotoxicity associated with oral diazepam in 12 cats. J Vet Int Med 1995; 9:194-197.
 
127.  Kantrowitz LB, Peterson ME, Trepanier LA, et al. Serum total thyroxine, total triiodothyronine, free thyroxine, and thyrotropin concentrations in epileptic dogs treated with anticonvulsants. J Am Vet Med Assoc 1999; 214:1804-1808. - PubMed -
 
128.  Gaskill CL, Burton SA, Gelens HCJ, et al. Changes in thyroxine and thyroid-stimulating hormone concentrations in epileptic dogs recieving phenobarbital for one year. J Vet Pharmacol Ther 2000; 23:243-249. - PubMed -
 
129.  Gascill CL, Burton SA, Gelens HCJ, et al. Effects on serum thyroxine and thyroid stimulating hormone concentrations in epileptic dogs. J Am Vet Med Assoc 1999; 215:489-496. - PubMed -
 
130.  Chauvet AE, Feldman EC, Kass PH. Effects of phenobarbital administration on results of serum biochemical analyses and adrenocortical function test in epileptic dogs. J Am Vet Med Assoc 1995; 207:1305-1307. - PubMed -
 
131.  Foster SF, Church DB, Watson ADJ. Effects of phenobarbitone on serum biochemical tests in dogs. Aust Vet J 2000; 78:23-26. - PubMed -
 
132.  Jacobs G, Calvert C, Kaufman A. Neutropenia and trombocytopenia in three dogs treated with anticonvulsants. J Am Vet Med Assoc 1998; 212:681-684. - PubMed -
 
133.  Hess RS, Kass PH, Van Winkle TJ, et al. Evaluation of risk factors for fatal acute pancreatitis in dogs. J Am Vet Med Assoc 1999; 214:46-51. - PubMed -
 
134.  Gaskill CL, Cribb AE. Pancreatitis associated with potassium bromide/phenobarbital combination therapy in epileptic dogs. Can Vet J 2000; 41:555-558. - PubMed -
 
135.  Bagley RS, Baszler TV, Harrington ML, et al. Clinical effect of longitudinal division of the corpus callosum in normal dogs. Vet Surg 1995; 24:122-127. - PubMed -
 
136.  Bagley RS, Harrington ML, Moore MP. Surgical treatments for seizure: Adaptability for dogs. Vet Clin North Am Small Anim Pract 1996; 26:827-842. - PubMed -
 
137.  Koblik PD, LeCouteur RE, Higgins RJ, et al. CT guided brain biopsy using a modified perolus mark III stereotactic system: experience with 50 dogs. Vet Radiol Ultrasound 1999:;40:434-440. - PubMed -
 
138.  Woodbury DM, Woodbury JW. Effects of vagal stimulation on experimentally induces seizures in rats. Epilepsia 1990; 31 (suppl 2): S7-S19. - PubMed -
 
139.  The vagus nerve stimulation study group. A randomised controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures. Neurology 1995; 45:224-230. - PubMed -
 
140.  Schachter SC. Vagal nerve stimulation. In: Smith D, Schacter SC eds. Epilepsy. Problem solving in clinical practice. London: Martin Dunitz Ltd, 2000; 439-453. - Available from amazon.com -
 
141.  Speciale J, Stahlbrodt JE. Use of ocular compression to induce vagal stimulation and aid in controlling seizures in seven dogs. J Am Vet Med Assoc 1999; 214:663-665. - PubMed -
 
142.  Puchowicz MA, Smith CL, Bomont C, et al. Dog model of therapeutic ketosis induced by oral administration of R,S-1,3-butanediol diacetoacetate. J Nutr Biochem 2000; 11:281-287. - PubMed -
 
143.  Bateman SW, Parent JM. Clinical findings, treatment, and outcome of dogs with status epilepticus or cluster seizures: 156 cases (1990-1995). J Am Vet Med Assoc 1999; 215:1463-1468. - PubMed -
 
144.  Saito M, Munana, KR, Sharp N, et al. Risk factors for development of status epilepticus in dogs with idiopathic epilepsy and effects of status epilepticus on outcome and survival time. J Am Vet Med Assoc 2001; 219:618-623. - PubMed -
 
145.  Working group on status epilepticus. Treatment of convulsive status epilepticus: recommendations of the epilepsy foundation of Americas working group on status epilepticus. J Am Med Assoc 1993; 270:854-859. - PubMed -
 
146.  Lowenstein DH, Bleck T, Macdonald RL. It’s time to revise the definition of status epilepticus. Epilepsia 1999; 40:120-122.
 
147.  Meldrum BS, Horton RW. Physiology of status epilepticus in primates. Arc Neurol 1973; 28:1-9.
 
148.  Meldrum BS. Epileptic brain damage: a consequence and a cause of seizures. Neuropathol Appl Neurobiol 1997; 23:185-202. - PubMed -
 
149.  Meldrum BS. Metabolic factors during prolonged seizures and their relation to nerve cell death. Adv Neurol 1983; 34:261-275.
 
150.  Shorvon S. The managenment of status epilepticus. In: Hopkins A, Shorvon S, Cascino G eds. Epilepsy, 2nd. ed. London: Chapman & Hall 1995; 331-345. - Available from amazon.com -
 
151.  Brown JK, Hussain IHMI. Status epilepticus 1: Pathogenesis. Develop Med Child Neurol 1991; 33:3-17.
 
152.  Fountain NB, Lothman EW. Patophysiology of status epilepticus. J Clin Neurophysiol 1995; 12:326-342. - PubMed -
 
153.  Shorvon S. Tonic-clonic status epilepticus. J Neurol Neurosurg Psychiatry 1993:56:125-134.
 
154.  Lösher W, Frey HH. Pharmacokinetics of diazepam in the dog. Arch Int Phamacodyn 1981; 254:180-195. - PubMed -
 
155.  Colter S, Gustafson JH, Colburn WA. Pharmacokinetics of diazepam and nordiazepam in the cat. J Pharm Sci 1984; 73:348-351. - PubMed -
 
156.  Podell M, Wagner SO, Sama RA. Lorazepam concentrations in plasma following its intravenous and rectal administration in dogs. J Vet Pharmacol Therap 1998; 21:158-160.
 
157.  Podell M. The use of diazepam per rectum at home for the acute management of cluster seizures in dogs. J Vet Int Med 1995; 8:68-74. - PubMed -
 
158.  Platt S, Randell SC, Scott KC et al. Comparison of plasma benzodiazepine concentrations following intranasal and intravenous administration of diazepam in dogs. Am J Vet Res 2000; 61:651-654. - PubMed -
 
159.  Kapur J, Macdonald RL. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABA-A receptors. J Neurosci 1997; 17:7532-7540. - PubMed -
 
160.  Wagner SO, Sams RA, Podell M. Chronic phenobarbital therapy reduces plasma benzodiazepine concentrations after intravenous and rectal administration of diazepam in the dog. J Vet Pharmacol Therap 1998; 21:335-341. - PubMed -
 
161.  Smedile LE, Duke T, Taylor SM. Excitatory movements in a dog following propofol anesthesia. J Am Anim Hosp Assoc 1996; 32:365-368. - PubMed -
 
162.  Stefen F, Grasmueck S. Propofol for treatment of refractory seizures in dogs and cats with intracranial disorders. J Small Anim Pract 2000; 41:496-499. - PubMed -
 
163.  Oberbauer AM, Grossman DI, Irion DN et al. The genetics of epilepsy in the Belgian Tervuren dog. J Hered 2003;94:57-63. - PubMed -
 
164.  Patterson EE, Mickelson JR, Da Y et al. Clinical Characteristics and inheritance of idiopathic epilepsy in Vizslas. J Vet Intern Med 2003;17:319-325. - PubMed -
 
165.  Licht BG, Licht MH, Harper KM et al. Clinical presentations of naturally occurring seizures: Similarities to human seizures. Epilepsy Behav 2003;3:460-470. - PubMed -
 
166.  Berendt M, Dam M. Re: Clinical presentations of naturally occurring canine seizures: similarities to human seizures. Epilepsy Behav 2003;4:198-201.
 
167.  Hasegawa D, Fujita M, Nakamura S. Electrocorticographic and histological findings in a Shetland Sheepdog with intractable epilepsy. J Vet Med Sci 2002;64:277-279. - PubMed -
 
168.  Bush WW, Barr CS, Darrin EW et al. Results of cerebrospinal fluid analysis, neurological examination findings, and age at the onset of seizures as predictors for results of magnetic resonance imaging of the brain in dogs examined because of seizures: 115 cases (1992-2000). J Am Vet Med Assoc 2002;220:781-784. - PubMed -
 
169.  Boothe DM, George KL, Couch P. Disposition and clinical use of bromide in cats. J Am Vet Med Assoc 2002;221:1131-1135. - PubMed -
 
170.  Paull LC, Scott-Moncrieff JC, DeNicola DB. Effect of anticonvulsant dosages of potassium bromide on thyroid function and morphology in dogs. J Am Anim Hosp Assoc 2003;39:193-202. - PubMed -
 
171.  Hojo T, Ohno R, Shimoda M et al. Enzyme and plasma protein induction by multiple oral administrations of phenobarbital at a therapeutic dosage regimen in dogs. J Vet Pharmacol Ther 2002;64:121-127. - PubMed -
 
172.  Munana KR, Vitec SM, Tarver WB et al. Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs. J Am Vet Med Assoc 2002;221:977-983. - PubMed -
 
173.  Platt SR, Haag M. Canine status epilepticus: a retrospective study of 50 cases. J Small Anim Pract 2002;43:151-153. - PubMed -
 
174.  Jefferys JGR. Models and mechanisms of experimental epilepsies. Epilepsia 2003; 44(Suppl.12):44-50. - PubMed -
 
175.  Abramson CJ, Platt SR, Jacobs C et al. L-2-Hydroxyglutaric aciduria in staffordshire bull terriers. J Vet Int Med 2003; 17:551-556. - PubMed -
 
176.  Rossmeisl JH, Duncan R, Fox J et al. Neuronal ceroid-lipofuscinosis in a labrador retriever. J Vet Diagn Invest 2003; 15:557-560. - PubMed -
 
177.  Barnes HL, Chrisman CL, Farina et al. Clinical evaluation of rabies meningoencephalomyelitis in a dog. J Am Anim Hosp Assoc 2003; 39:547-550. - PubMed -
 
178.  Troxel MT, Vite CH, Van Winkle TJ et al. Feline intracranial neoplasia: retrospective review of 160 cases (1985-2001). J Vet Int Med 2003; 17:850-859. - PubMed -
 
179.  Kitagawa M, Kanayama K, Sakai T. Quadrigeminal cisterna arachnoid cyst diagnosed by MRI in five dogs. Aust Vet J 2003; 81:340-343. - PubMed -
 
180.  Pellegrino FC, Sica RE. Canine electroencephalographic recording technique: findings in normal and epileptic dogs. Clin Neurophysiol 2004; 115:477-487. - PubMed -
 
181.  Aitken MM, Hall E, Scott L et al. Liver related biachemical changes in the serum of dogs being treated with phenobarbitone. Vet Rec 2003; 153:13-16. - PubMed -
 
182.  March PA, Hillier A, Weisbrode SE et al. Superficial necrolytic dermatitis in 11 dogs with a history of phenobarbital administration. J Vet Int Med 2004; 18:65-74. - PubMed -

 
 
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