Macule Definition: A focal, circumscribed, nonpalpable change in color <1 cm (when it is larger, it is termed a patch). Pathogenesis: Pigmentation change due to decreased or increased melanin production, erythema due to inflammation or local hemorrhage caused by trauma or vasculitis.

Figure 1-1a. Macule - Definition: A focal, circumscribed, nonpalpable change in color <1 cm (when it is larger, it is termed a patch). Pathogenesis: Pigmentation change due to decreased or increased melanin production, erythema due to inflammation or local hemorrhage caused by trauma or vasculitis.

Mueller, R.S. Dermatologic Examination. In: Mueller R.S. (Ed.), Dermatology for the Small Animal Practitioner. Ithaca: International Veterinary Information Service (www.ivis.org), 2006; Document No. A3704.0206.(Accessed: 20 Aug 2017).